課程資訊
課程名稱
進階動物生物技術
Advanced Animal Biotechnology 
開課學期
100-1 
授課對象
生物資源暨農學院  生物科技研究所  
授課教師
宋麗英 
課號
Biot5007 
課程識別碼
642EU0100 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期三2,3,4(9:10~12:10) 
上課地點
生技所410 
備註
本課程以英語授課。
限學士班三年級以上
總人數上限:20人
外系人數限制:15人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1001adv_ani_biotech 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

The objectives of this course are 1) to provide graduate students with an overview of recent developments in animal biotechnology; 2) to improve graduate students' presentation skills. After extensive review and discussion of various biotechnologies, each student will be asked to give a presentation in the area other than their own research. I will meet with all students individually several times during their literature search, preparation of presentation outline and presentation practice. Lab demonstrations of basic embryology techniques will be included as well. Guest speakers will plan to invite for the lectures as necessary.  

課程目標
1. Introduction and overview of animal biotechnology
2. Folliculogenesis, oogenesis, embryogenesis
3. In vitro maturation/fertilization and embryo culture — state of the art
4. Embryo cryopreservation
5. Genetic micromanipulations of embryos
6. DNA identifications of transgenetic
7. Transgenic animals as organ donors (xenotransplantation)
8. Human Assisted Reproductive Technology (ART)
9. Sperm and embryo sexing
10. Somatic cell nuclear transfer- state of the art
11. Telomere, telomerase and gene reprogramming in age of cloned animal
12. X chromosome inactivation
13. Genetic imprinting
14. Functional genomics in humans and animals-state of the art
15. Introduction of embryonic stem cells
16. Introduction of adult stem cells
17. Therapeutic cloning— state of the art 
課程要求
 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
1. Developmental Biology, eighth edition, Scott F. Gibert, Sinauer Associates, Inc., USA
2. Reproduction in Farm Animals, seventh edition, E.S.E.Hafez and B. Hafez, Lippincott Williams and Wilkins
3. Pathways to pregnancy and parturition, second edition, P.L. Senger, Current Conceptions, Inc. USA
4. PubMed, www.pubmed.gov 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
Week 1
9/14  Introduction and overview of animal biotechnology  
Week 2
9/21  Folliculogenesis, oogenesis and embryogenesis 
Week 3
9/28  In vitro maturation/ fertilization and embryo culture - state of the art 
Week 4
10/05  Sperm and embryo sexing - state of the art 
Week 5
10/12  Oocyte and embryo cryopreservation 
Week 6
10/19  Human IVF/ART, genetic diagnosis (PGD) 
Week 7
10/26  Somatic cell nuclear transfer - state of the art 
Week 8
11/02  Telomere, telomerase and gene reprogramming in age cloned animal (Dr. Xu) 
Week 9
11/09  Mid-exam
Student presentation –
 
Week 10
11/16  Student presentation –  
Week 11
11/23  Epigenetic reprogramming in cloned embryos 
Week 12
11/30  Gene targeting using somatic cell nuclear transfer in farm animals 
Week 13
12/07  Embryonic stem cells  
Week 14
12/14  Adult stem cells – Spermatogonial stem cells 
Week 15
12/21  Induced pluripoent stem cells 
Week 16
12/28  Student presentation –  
Week 17
1/04  Student presentation –